The Art of Natural Dressage

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PostPosted: Wed Dec 02, 2009 2:04 am 
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Joined: Fri Sep 21, 2007 4:10 am
Posts: 3688
Location: Pacific Northwest U.S.
I have just this morning ordered up bulk quantities of both Turmeric and Cinnamon (another of my favorite healthy spices).

I use rather a lot of both (Turmeric more recently than cinnamon) and believe I detect an improvement in at least two areas of health issues for me personally: gut health, and peripheral nerve recovery, my feet more specifically in the latter instance.

Two years ago I could not walk 100 ft or more without debilitating pain. Today I can wander up toe half a mile before being incapacitated (though I can still walk).

I'll leave the more sensitive issues of gut health out of this forum, at least in terms of details. Suffice to say that I enjoy the ability to be able to eat things these days with less discomfort and dis-accommodation than ever before. In other words, I don't have to have a rest room facility nearby any more after a meal.

I like this source of spices and herbs quite a bit already, even without having received the shipment from them and sampled it. They have a very impressive way of educating one to the materials they sell. I found out why cinnamon sometimes takes great and other times I don't like it. There is different quality grown in different places with various handling characteristics that can improve or lessen the quality and taste.

I'll discuss this more in this subject thread when I know more about this company and the products.

Nettlepatch Farm

Love is Trust, trust is All
So say Don, Altea, and Bonnie the Wonder Filly.

PostPosted: Wed Jan 06, 2010 2:11 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
windhorsesue, keep up the green tea, turmeric, chocolate and wine....

How Plants Protect Us From Disease
ScienceDaily (Apr. 27, 2009) — Everyday foods, beverages, and spices contain healthful compounds that help us fight harmful inflammation. And, in doing that, these phytochemicals—the resveratrol in red wine or the catechins in green, white and black teas, for instance—may also reduce our risk of diseases associated with chronic inflammation, including cancer and diabetes.

At the Agricultural Research Service (ARS) Western Human Nutrition Research Center in Davis, Calif., research molecular biologist Daniel H. Hwang conducts studies to solve the complex puzzle of precisely how phytochemicals fight inflammation. His investigations with cells cultured in his laboratory have uncovered probable modes of action used by phytochemicals from red wine, green tea, garlic, curcumin and cinnamon.

Hwang's team has found, for example, that phytochemicals can interfere with the normal flow of certain chemical signals or messages sent to and from cells involved in chronic inflammation. The messages these cells send are in the form of proteins. In particular, his group is closely examining proteins known as TLRs (short for "Toll-Like Receptors") and NODs (an abbreviation for the tongue-twisting "nucleotide binding oligomerization domain containing proteins").

Their experiments show that certain phytochemicals can interfere with messages that, if unimpeded, could travel from TLRs and NODs, reaching and activating genes that can trigger an inflammatory response.

The studies suggest that different phytochemicals have different ways of interfering with these messages. For example, curcumin can undermine certain TLRs when a specific part of curcumin's chemical structure reacts with what are known as "sulfhydryl groups" in TLRs.

But resveratrol, found in red grapes, has a different set of targets. Hwang's experiments suggest that resveratrol interferes with molecules called "TBK1" and "RIP1." If unimpeded, these molecules would help convey signals to and from TLRs.

Susie xx

PostPosted: Wed Jan 06, 2010 2:21 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
The Boston Globe
(There is newer research now published but this is written in a chatty style compared to the Gov't papers, USA was hoping all citizens would take 1/2 a teaspoon of Cinnamon daily to reduce the health bills especially with increasing obesity problems cauising diabetes in so many people, if they added turmeric, tea, wine, chocolate and perhaps made food portions smaller and had a day a week fasting????.)
Cinnamon joins cholesterol battle
By Judy Foreman | August 24, 2004

The next drug in your medicine cabinet might come from the spice aisle of the grocery store.

Although research is still preliminary, doctors and researchers are getting excited about the diabetes and cholesterol-fighting potential of cinnamon.

Cinnamon probably "can't harm in small doses, it may help and it's not adding calories," said Melinda Maryniuk, a senior dietician at the Joslin Diabetes Center in Boston.

A small study completed last year on the possible health benefits of cinnamon was "very exciting and promising," according to Dr. Andrew Greenberg, director of the obesity metabolism laboratory at Tufts University, who is so intrigued he has begun studying it himself.

The 40-day study, of 60 people in Pakistan with Type 2 diabetes, found that one gram a day of cinnamon -- one-fourth of a teaspoon twice daily -- significantly lowered the subjects' blood sugar, triglycerides (fatty acids in the blood), LDL (or "bad") cholesterol, and total cholesterol.

Don't go bananas with this, of course. In high doses -- no one knows exactly how much -- cinnamon is believed to be toxic, according to Richard Anderson, a researcher at the Beltsville Human Nutrition Research Center in Maryland, part of the US Department of Agriculture, who conducted the study in Pakistan.

And don't substitute cinnamon for prescription medication whose benefits are well established.

"Cinnamon is a lot less effective than statins" at lowering cholesterol levels in the blood, according to Dr. Frank Sacks, a physician at Brigham and Women's Hospital and professor of nutrition at the Harvard School of Public Health. Statins have been tested in rigorous studies on 70,000 people for five years or more. Compared to that, he said, the research on cinnamon is weak.

"There are certainly substances in plants that have very strong biological effects, so the concept is fine," he said. And plant derivatives "are being intensively researched at many places -- that's a hot topic."

But it's also "a little weird," he said, that the USDA study found that the beneficial effects of cinnamon lasted for at least 20 days after people stopped taking it. "I don't know of any drug or product whose effects persist for 20 days."

For diabetics, cinnamon "does much the same thing as insulin" biochemically, said Don Graves, an adjunct professor of biochemistry at the University of California in Santa Barbara who has studied how cinnamon works in the body.

In Type 2 diabetes, the problem is that insulin no longer does a good job of escorting sugar into cells, said Anderson of the USDA. Cinnamon "makes cells more sensitive to the insulin that is available," he said.

An active ingredient in cinnamon, proanthocyanidin, worms its way inside cells, where it activates the insulin receptor. Once this receptor is activated, whether by insulin or cinnamon, chemical reactions occur allowing the cell to use energy from sugar.

A few other caveats are in order. If you have Type 2 diabetes, you should monitor your blood sugar carefully when adding cinnamon because the spice may intensify the effects of insulin medication -- or better yet, talk to your doctor first.

And don't use the good news about cinnamon to indulge regularly in calorie-laden cinnamon buns or muffins, warned Alice Lichtenstein, a professor at the Friedman School of Nutrition Science and Policy at Tufts University. Gaining weight would be worse for your health than not eating cinnamon, she said.

Finally, there may be an indirect health benefit to be had from cinnamon, according to Taiwanese scientists writing in the July 14 issue of Agriculture and Food Chemistry. Cinnamon oil, they found, kills mosquito larvae more effectively than DEET, a common pesticide and mosquito repellent. The next step is to test it against adult mosquitoes.

Susie xx

PostPosted: Wed Jan 06, 2010 2:40 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border

Adding a little spice to your horse’s diet can
help in coping with insulin resistance
By Gloria Garland L.Ac, Dipl. Ac. & CH.

Insulin resistance (IR) is becoming an all too common
problem among horses. Cinnamon, a spice
found in every kitchen cupboard, may offer help.
IR what is it and why is it a problem?
Insulin resistance (IR) is the inability of the body to
remove blood sugar (glucose) from circulation. Insulin
resistance can lead to the development of several related
diseases like laminitis and equine Cushing’s disease.
Excess bodyweight, lack of exercise and/or a modern
diet high in sugars and starch (found in high amounts in
many commercially processed feeds) may predispose a
horse to develop insulin resistance.
Typically, an IR horse is an easy keeper with a cresty
neck or unusual fat deposits on its sides or tail head. IR
horses often get warm feet, become tender footed or
have a tendency toward laminitis.
Cinnamon - How it works
Very simply, cinnamon helps enable cells
to recognize and respond to insulin, the
hormone that transports glucose (sugar)
from the blood and deposits it into cells.
Methylhydroxy chalcone polymer
(MHCP), a compound in cinnamon, makes
cells more responsive to insulin by activating
the enzyme that causes insulin to bind
to cells and by inhibiting the enzyme that
blocks this process.

Many types and varieties of cinnamon
The most potent varieties of cinnamon are from South
East Asia, especially those from Viet Nam. The two
types of cinnamon used in traditional Chinese medicine
are: Rou gui (Cortex cinnamomum cassia), specifically
the bark of the tree, and the tips and twigs of the tree
called Gui zhi (Ramulus cinnamomum cassia). The cinnamon
in your spice rack probably originated from Indonesia
or Mexico and tends to be milder in flavor and
Separately both types of cinnamon are useful in the
treatment of IR but optimal effects are achieved when
the two are paired. Rou gui more strongly simulates the
action of insulin and activates insulin receptors while
Gui zhi has the effect of stimulating blood flow to the
extremities and promoting
microcirculation in the capillaries
– especially helpful in the
case of chronically laminitic horses.

When not to use Cinnamon
Cinnamon is not recommended during fevers or bleeding
and with high insulin sensitivity (EPSSM horse).

Used in conjunction with a low sugar, low starch diet
and exercise, cinnamon offers help to IR horses.

Chinese herbal supplements should be used properly
and thoughtfully under the guidance of a licensed Chinese
herbalist. Traditional Chinese Medicine (TCM),
used properly, is an adjunctive therapy and, therefore,
complementary to veterinary treatment. Information
presented here is not intended to replace proper veterinary
diagnosis or treatment and should not be used for
that purpose.

Susie xx

PostPosted: Wed Jan 06, 2010 2:55 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
Turmeric will help with laminitis/founder/Insulin Resistance by helping to maintain a healthy gut, which is where these problems begin before they show in sore feet or increased weight.
Linseed/Flax seed offers natural oils high in balanced ratio Omega and with the benefit of copper.
Magnesium Oxide is often low in pasture analysis and can be beneficial to metabolism.

Below is a UK vet advice:
Laminitis and Founder
October 2007

According to the National Animal Health Monitoring System (NAHMS) 2000 report, 13% of all horse operations had a horse with laminitis in the previous year and 4.7% of these died or were euthanized. That makes laminitis second only to colic as a leading killer of horses.
What is laminitis (and founder)?
Inside the horse’s hoof is a bone called the coffin bone. It’s attached to the hoof by tiny interlocking fingers, or laminae. A complex sequence of events occurs during laminitis, but the key events are inflammation of these laminae (therefore the name laminitis), their death and the death of cells around them. When these tissues die, the coffin bone is no longer properly supported in the hoof. Then, forces from bearing weight on the ground as well as from tendons pulling upward on the bone can cause it to rotate or sink in the hoof. When structural damage like this occurs, the horse is said to have "foundered."
What causes laminitis?
According to Rustin Moore, DVM, PhD, Dipl. ACVS, who shared his research at the most recent Bluegrass Laminitis Symposium held January 2007 in Louisville, KY, laminitis often occurs because of other inflammatory conditions in the body, such as:
Pasture (carbohydrate) overload
Grain overload
Endotoxins in the blood
Uterine infection or retained placenta
Metabolic disturbances such as insulin resistance
Excess weight-bearing on a supporting limb (opposite a limb with a severe injury)
Infection of the blood (septicemia)
Infection of the lungs
Enterocolitis (inflammation of the small intestine and colon)

What are the signs of laminitis?
Owners should learn to recognize the following, very characteristic appearance of a laminitic horse:

Shifting of weight from foot to foot
Slight stiffness of gait
Reluctance to move
Classic founder stance: all four feet forward , so hind feet carry more weight
Warm feet, bounding digital pulse
Sweating, high heart and respiratory rates
Lying down and not wanting to get up

Any horse showing these signs should be seen immediately by a veterinarian to confirm the diagnosis and start emergency treatment which may not only save the horse’s performance career, but also his life.

How is laminitis treated?
The goal of treating laminitis is to first treat the primary disease that caused it, then try to limit the inflammation and structural damage that is occurring. Because the exact sequence of events leading to damage in the foot has not been completely figured out, treatment can be controversial. Most agree however, that a nonsteroidal anti-inflammatory (NSAID) medication like phenylbutazone or "bute" should immediately be given to reduce inflammation, since this seems to be a common factor in all laminitis cases. Other medications that may be used include vasodilators like acepromazine, anticoagulants, and antiendotoxins.

The next step is providing mechanical support to the foot, to ensure even blood flow to all the tissues and try to prevent rotation or sinking. Some do this by stalling the horse in sand, which provides soft, even support across the whole bottom of the foot. Others prefer to attach devices directly to the bottom of the foot to provide "arch support," to elevate the horse’s heels, and to encourage breakover in a certain area of the foot. Again, most agree that stall rest is critical, at least for the first few days.

Obviously the veterinarian and farrier must work closely together to provide treatment to the laminitic horse both in the acute and chronic phases. Baseline and follow-up radiographs allow the healthcare team to measure the damage and accurately place and replace support devices.
Can laminitis be prevented?
Approximately half of the horses that develop laminitis are on pasture when the disease develops. There are two reasons for this.
Certain grasses under certain conditions have high levels of fructans, a specific sugar that has been shown to cause laminitis.
Horses with insulin resistance (IR), a component of Equine Metabolic Syndrome, are predisposed to laminitis and pasture acts as a trigger factor.
For these reasons, horses that have developed laminitis from pasture or that have been diagnosed with IR should be allowed limited to no grazing. Horses with IR should also not have sweet feed, treats with sugar, or anything with molasses in it. An appropriate diet for a horse prone to laminitis from sugar is grass or alfalfa hay and a ration balancer or multi-vitamin/mineral instead of grain.

Additional strategies are available. For example, research suggests supplementing with essential fatty acids may prevent laminitis caused by pasture carbohydrate overload. The prescription medication Thyro-L (levothyroxine) is currently being investigated as a treatment for insulin resistance toward a defense against laminitis. Certain nutrients—chromium, magnesium, cinnamon and others—have been shown to help support healthy metabolic function and may also be useful.

Laminitis and Founder
By: Lydia F. Gray, DVM, MA
SmartPak Staff Veterinarian and Medical Director
October 2007

Susie xx

PostPosted: Fri Jan 15, 2010 12:50 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border

Studies are showing that turmeric may help fight breast cancer, colon cancer, multiple myeloma and possibly lymphoma. Moreover, turmeric is a great anti-inflammatory substitute for NSAID's such as ibuprofen, etc.

Turmeric is a yellow spice used widely in Indian cooking. US researchers have found that curcumin, an active compound found in turmeric, helped stop the spread of breast cancer tumour cells to the lungs in mice.

Researchers from the University of Texas M.D. Anderson Cancer Center presented their findings regarding curcumin found in the spice turmeric in Philadelphia at the U.S. Defense Department's "Era of Hope" Breast Cancer Research Program.

"Tests have already started in people, too", said Bharat Aggarwal of the Department of Experimental Therapeutics at the University of Texas Anderson Cancer Centre in Houston, who led the study. Here you don't need to worry about safety. The only thing we have to worry about is efficacy," Aggarwal said in a telephone interview. "Curcumin, as you know, is very much an essential part of the Indian diet," he added.

"What's exciting about this agent is that it seems to have both chemopreventive and therapeutic properties. If we can demonstrate that it is efficacious in humans, it could be of tremendous value, but we're a long way from being able to make any recommendations yet," Aggarwal said.

Earlier research showed that curcumin, which acts as an antioxidant, can help prevent tumors from forming in the laboratory. For their study, Aggarwal and colleagues injected mice with human breast cancer cells in a batch of cells grown from a patient whose cancer had spread to the lungs. The resulting tumors were allowed to grow, and then surgically removed, to simulate a mastectomy, Aggarwal said. Then the mice either got no additional treatment; curcumin alone; the cancer drug paclitaxel, which is sold under the brand name Taxol; or curcumin plus Taxol.

Half the mice in the curcumin-only group and 22 per cent of those in the curcumin plus Taxol group had evidence of breast cancer that had spread to the lungs, Aggarwal said in a study to be presented to a breast cancer research meeting in Philadelphia. But 75 per cent of animals that got Taxol alone and 95 per cent of those that got no treatment developed lung tumours. Aggarwal said earlier studies suggest that people who eat diets rich in turmeric have lower rates of breast cancer, prostate cancer, lung cancer and colon cancer.

His team would like to try giving curcumin to women who know they have a high risk of breast cancer such as those who have a mother or sister with the disease. Curcumin could be of "tremendous value" if it's shown to be effective in humans, "but we're a long way from being able to make any recommendations yet, says researcher Bharat Aggarwal, PhD, in a news release.

Some alternative doctors have started to prescribe extracted curcumin along with either warm coconut milk or heavy cream (better absorbed that way according to Dr. Stephen Martin PhD of One of my breast cancer clients takes 1 Tbs (5 grams) with ¼ cup of warm coconut milk twice a day, but you may want to consult with Dr. Martin regarding proper dosages.

For more recommendations,dosages, and information on turmeric go to:


John Hopkins researchers published in the August issue of Clinical Gastroenterology and Hepatology, the results of a small study with five patients, who have an inherited form of precancerous polyps in the lower bowel known as familial adenomatous polyposis, of FAP.

These patients were treated over an average of six months with regular doses of curcumin, the chemical found in turmeric, and quercetin, an antioxidant in onions. The average number of polyps dropped 60.4 percent, and the average size dropped by 50.9 percent, according to a team led by gastroenterologist Francis M. Giardiello, a professor at the School of Medicine, and Marcia Cruz-Correa, a visiting professor from the University of Puerto Rico School of Medicine.

"We believe this is the first proof of principle that these substances have significant effects in patients with FAP," Giardiello said.

In the trial, five patients were selected from the Cleveland Clinic Florida. All had previously had their colons surgically removed; four of the five retained the rectums, whereas the remaining patient had had both colon and rectum removed and part of the small intestine adapted to serve as colon and rectum. All patients had five or more adenomas in their lower intestinal tract. None of the patients had taken NSAIDS for more than one week during the three months leading up to the study.

Participants were examined using a flexible sigmoidoscope before treatment was initiated and at three-month intervals (range three to nine months) during treatment. Number and size of polyps were examined at each visit.

Each patient received 480 milligrams of curcumin and 20 milligrams of quercetin orally three times a day for six months and was told not to use NSAIDs for the duration of the study. Three patients followed treatment as prescribed. One patient did not follow the scheduled treatment doses between months three and six and was continued on therapy until the ninth month. Another patient dropped out of the study after the third month.

A decrease in polyp number was observed in four of the five patients at three months and four of the four patients at six months.

Side effects were minimal. One patient reported slight nausea and a sour taste within a couple of hours of taking the pill, an effect that went away within three days, and a second patient had mild diarrhea for five days.


for cancer prevention therapies and complementary treatments see

Susie xx

PostPosted: Fri Jan 15, 2010 1:43 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
This organisation have to take a cautious approach to making recommendations for alternative therapies which have not been licenced by the Pharmacuetical giant organisations for use in human medicine. The warning about taking capsules or bottled extract is sensible as some sellers may include any substance to form a tablet. However as Cancer Research UK suggests, for use in cooking or drinking, using the pure powder these worries are overcome.

Can turmeric prevent bowel cancer?
Turmeric is a spice that is often used as a food flavouring in Asian dishes. It grows in many tropical countries like India. It has also been used for many years in some herbal remedies. ... wel-cancer

A trial looking at curcumin to treat Barrett’s oesophagus
This trial is looking at a spice called curcumin to see if it can treat Barrett’s oesophagus. ... oesophagus

Turmeric is a yellow spice used as a flavouring in Asian dishes. It is part of the ginger family of plants and grows in many tropical countries, such as India. ... y/turmeric

A study looking at curcumin to help prevent bowel cancer
This study is looking at the possibility of giving curcumin capsules to people with bowel cancer or bowel polyps to help prevent bowel cancer growing or coming back. ... wel-cancer

Tube feeding is the giving of liquid food through a tube. It can be a tube from the nose to the stomach (nasogastric tube). O it can be a tube that goes directly into the stomach from the outside (a gastrostomy tube). ... ?letter=Tu

Research into preventing and diagnosing bowel cancer
This page tells you about research into preventing bowel cancer and finding better ways of diagnosing it. ... wel-cancer

Susie xx

PostPosted: Fri Jan 15, 2010 1:50 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
Dr. Andrew Weil's site
Q Turmeric for Breast Cancer Prevention?

Is it true that turmeric can prevent breast cancer? What can you tell me about this?

A Answer (Published 12/2/2005)

Turmeric (Curcuma longa) is the yellow spice most familiar in Indian curries and found in American prepared mustard. People whose diets are rich in turmeric have lower rates of breast cancer as well as prostate, lung and colon cancers, and recent research at the M.D. Anderson Cancer Center in Houston suggests that curcumin, an active component in turmeric, may help prevent the spread of breast cancer. In studies of mice, researchers found that curcumin helped stop the metastasis of breast cancer cells to the lung. Human studies following up on this finding are now in progress.

In the M.D. Anderson study, researchers injected mice with breast cancer cells from a woman whose disease had spread to her lungs. The cells began to grow in the mice and then were surgically removed. The mice then were divided into four groups: one got no treatment, one got curcumin, one got the cancer drug Taxol and the fourth group got curcumin plus Taxol. Cancer spread to the lungs among half the mice in the curcumin-only group and 22 percent of those in the curcumin/Taxol group. The other groups fared far worse: among the mice that received Taxol alone 75 percent developed lung tumors; and the cancer spread to the lungs among 95 percent of the mice who were given no treatment.

While these results are exciting, we don't know yet if curcumin plus Taxol will be as effective in humans. However, the researchers were impressed enough to suggest that it might be worthwhile to give curcumin to women at high risk of breast cancer because of a family history of the disease.

My preference is for whole turmeric rather than isolated curcumin, because I believe in the synergy of all active elements in botanical medicines. I wish researchers would get off the reductionistic bandwagon and come around to appreciate the inherent complexity of nature. Whole turmeric extracts are the way to go; I always recommend them to patients rather than products containing isolated curcumin.

Turmeric is useful for all inflammatory disorders and for autoimmune conditions. It also may have a role in the prevention and treatment of Alzheimer's disease. (Elderly villagers in India appear to have the lowest rate of Alzheimer's in the world, perhaps due to the fact that Indians eat turmeric with almost every meal. Some animal studies have shown that curcumin blocked the formation and accumulation of the plaque that characterizes Alzheimer's.)

Overall, turmeric appears to have significant anti-inflammatory and cancer-protective effects. These seem most evident at doses well below pharmaceutical strength, which suggests that it would be wise to consume more foods spiced with turmeric. But getting enough in food is not easy for Westerners. We are not familiar with using it, and large amounts taste bitter. Other than supplements, the best way I've found to consume turmeric is in the form of a cold, unsweetened tea. This is a popular beverage in Okinawa, the island culture famed for health and longevity. Convenient, tasty, instant forms of turmeric tea are easy to get there. I'm working to make them available through this Web site. Stay tuned.

Andrew Weil, M.D.

Susie xx

PostPosted: Fri Jan 15, 2010 2:10 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border

The Health Benefits of Turmeric

Both from a culinary and a medical perspective, the common curry ingredient, turmeric, is one of the most important spices. Researchers have found that it has outstanding properties as an anti-cancer and anti-Alzheimer's agent. Moreover, a landmark survey of all foods in the USA (American Journal of Clinical Nutrition, July 2006) found that turmeric is one of the top five anti-oxidant foods. This makes it one of the most valuable foods that we can use to fight cancer, Alzheimer's disease, aging and conditions associated with free radical damage and oxidative stress.

Turmeric's principal compound, curcumin, is one of the most researched of all the spice compounds. Much of the research and interest in curcumin has centered on its role in preventing and treating breast cancer, but it has also been found to have protective effects against cancers of the bladder, stomach, uterus and cervix. When measured against other phytochemicals, curcumin exhibits at least a ten times greater chemoprotective potency against cancer than its closest rivals.

Turmeric and Cancer

Curcumin is known to protect against cancer through the following mechanisms.

Assists the body's natural tumor-suppressing mechanisms.
Destroys cancer cells by stimulating apoptosis (programmed cell death) in these cells thereby terminating the immortality so typical of cancer cell lines.
Halts tumor proliferation by inhibiting DNA synthesis in the cancer cells and disrupting their replication.
Inhibits the formation of the abnormal blood vessels that are essential for tumour growth.
One of turmeric's most promising uses is in the prevention and treatment of breast cancer. Most breast cancers are hormone dependent, requiring estrogen as a growth stimulant. Tamoxifen, which is one of the most used drugs in the treatment of breast cancer, works against this hormone-mediated process, interfering with estrogen's tumor stimulating effects. Curcumin exhibits its anti-estrongenic effects by blocking the estrogen-dependent receptors on tumor cells, thereby interrupting the stimulatory effects of estrogen and slowing tumor growth. Curcumin may be at least as effective as tamoxifen as an estrogen antagonist, with none of the attendant side effects of this drug.

Radiotherapy and chemotherapy are widely used, but imperfect treatments for cancer. Not only do they have serious, debilitating side effects, but tumor cells often develop resistance to these therapeutic modalities. They also activate COX-2 enzymes that are part of the inflammatory process underlying many cancers. Turmeric reduces the activation of COX-2 enzymes and sensitizes the tumor cells to both radiotherapy and chemotherapy, enhancing their therapeutic effects.

Apart from curcumin, other phytochemicals found in turmeric are also known to have chemoprotective effects. Therefore, when it comes to prevention, it is better to take the parent spice, turmeric, rather than the pure curcumin extract. However, the treatment of existing breast cancer may call for more specific dosages of curcumin, the administration of which would need to be supervised by a qualified health practitioner.

Alzheimer's (AD) and Parkinson's Diseases

Curcumin exhibits several properties that make it a valuable preventive agent for these two devastating and increasingly common diseases. Although turmeric is probably most effective as a preventive agent against these illnesses, it may also help by improving cognitive problems and inhibiting further deterioration of existing disease.

Curcumin works against neurodegenerative diseases via the following mechanisms:

The accumulation of amyloid protein in the brain is an important factor associated with Alzheimer's disease. Its deposition is associated with oxidative damage and inflammation in the brain tissues. Curcumin is both a potent antioxidant and anti-inflammatory agent and has been shown to suppress oxidative damage, inflammation and the deposition of damaging amyloid protein in the brain. It is possible that it may actually disaggregate existing amyloid plaques and, in so doing, could possibly reverse the course of the disease.
Another cause of amyloid deposition in the brain is probably due to the accumulation of certain metals, as higher concentrations of harmful metals have been found in the brains of AD sufferers that in non-AD individuals. Metal molecules that find their way into the brain can both induce amyloid aggregation and are directly toxic to brain cells. Certain chelating agents have shown promise in the treatment of Alzheimer's disease and curcumin's chelating properties enable it to assist the body in the removal of potentially toxic metals from the brain and other tissues.
The abnormal proliferation of the brain’s non-neuronal cells is another pathological process that is associated with the development of both Alzheimer's and Parkinson’s diseases. Curcumin prevents the proliferation of these cells which, if allowed to continue growing, cause damage to the brain’s neuronal tissue.

Inflammatory Diseases

Much of turmeric's anti-inflammatory potency can be attributed to curcumin, which is both an effective COX-2 inhibitor as well as a strong antioxidant. However, other phytochemicals found in turmeric, in particular the salicylates, also make a valuable contribution to its anti-inflammatory activities and thereby its preventive properties against arthritis, autoimmune disorders and the general health consequences of chronic systemic inflammation and degenerative diseases.


Copper and iron are both essential nutrients but if they accumulate in excessive quantities they can cause serious and sometimes irreversible inflammatory and oxidative damage to a variety of tissues. Curcumin is a powerful chelating agent for both metals, binding to the metal ions and allowing them to be safely excreted in the urine.

Traditional use and modern scientific research have shown that turmeric is one of the most valuable spices in our arsenal of disease fighting foods. Synergism between different spices enhances the bioavailability of important compounds such as curcumin. Therefore, to obtain optimum benefit from turmeric, it is important to take it with other common spices.

Those who are serious about maintaining a healthy lifestyle in order to enjoy a good quality of life and reduce the risk of acquiring conditions like Alzheimer's disease and cancer would do well to ensure a daily intake of this golden spice.

About The Author:
Keith Scott is a medical doctor who has a special interest in nutritional medicine. He has written several books on health related topics including Medicinal Seasonings, The Healing Power Of Spices and Natural Home Pharmacy. For more information about the preventive and therapeutic value of turmeric and other spices go to:

Susie xx

PostPosted: Fri Jan 15, 2010 2:12 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
From The American Cancer Society: ... tearea=ETO


Other common name(s): jiang huang, haridra, Indian saffron

Scientific/medical name(s): Curcuma longa, Curcuma domestica


Turmeric is a spice grown in India and other tropical regions of Asia. It has a long history of use in herbal remedies, particularly in China, India, and Indonesia. The root and rootstock, or rhizome, of the plant contain the active ingredient, curcumin. Curcumin is not related to cumin, which is a spice made from the seeds of a different plant.


Turmeric is a common food flavoring and coloring in Asian cooking. Animal and laboratory studies have found that curcumin, an antioxidant that is an active ingredient in turmeric, demonstrated some anticancer effects. However, clinical research is needed to determine curcumin's role in cancer prevention and treatment in humans. Several types of cancer cells are inhibited by curcumin in the laboratory, and curcumin slows the spread of some cancers in some animal studies.

Curcumin is being studied to find out whether it helps other diseases such as arthritis, Alzheimer's disease, and stomach ulcers. It is also being studied to see whether it can help lower "bad cholesterol" and improve outcome in kidney transplants. A few early studies have been done in humans, but more human research is still needed to find out it curcumin can be effective in these uses.

How is it promoted for use?

Some researchers believe turmeric may prevent and slow the growth of a number of types of cancer, particularly tumors of the esophagus, mouth, intestines, stomach, breast, and skin. One researcher reported that curcumin, the active ingredient in turmeric, inhibited the formation of cancer-causing enzymes in rodents.

Turmeric is promoted mainly as an anti-inflammatory herbal remedy and is said to produce fewer side effects than commonly used pain relievers. Some practitioners prescribe turmeric to relieve inflammation caused by arthritis, muscle sprains, swelling, and pain caused by injuries or surgical incisions. It is also promoted as a treatment for rheumatism and as an antiseptic for cleaning wounds. Some proponents claim turmeric interferes with the actions of some viruses, including hepatitis and HIV.

Supporters also claim that turmeric protects against liver diseases, stimulates the gallbladder and circulatory systems, reduces cholesterol levels, dissolves blood clots, helps stop external and internal bleeding, and relieves painful menstruation and angina, chest pains that often occur with heart disease. It is also used as a remedy for digestive problems such as irritable bowel syndrome, colitis, Crohn's disease, and illnesses caused by toxins from parasites and bacteria.

What does it involve?

Turmeric root is on the Commission E (Germany's regulatory agency for herbs) list of approved herbs, and it is available in powdered form as a spice in most grocery stores. It can also be made into a tea or purchased as a tincture, capsule, or tablet. Ointments or pastes made from turmeric can be applied to the skin. Although there is no standardized dose for turmeric, some practitioners recommend taking a teaspoon with each meal. The dried root of turmeric normally contains from 3% to 5% curcumin. Today, many sellers market supplements that claim to be standardized to contain 95% curcumin compounds.

What is the history behind it?

The use of turmeric was described in traditional Chinese and Indian medicine as early as the seventh century AD. In various Asian folk medicine traditions, turmeric has been used to treat a long list of conditions, including diarrhea, fever, bronchitis, colds, parasitic worms, leprosy, and bladder and kidney inflammations. Herbalists have applied turmeric salve to bruises, leech bites, festering eye infections, mouth inflammations, skin conditions, and infected wounds. Some people inhale smoke from burning turmeric to relieve chronic coughs. Turmeric mixed with hot water and sugar is considered by some herbalists to be a remedy for colds.

In India and Malaysia, there is a custom of making turmeric paste to apply directly onto the skin, a practice now under study for the possibility that it may prevent skin cancer. The bright red forehead mark worn by some Hindu women is created by mixing turmeric with lime juice. Chefs frequently add turmeric to their creations because of its rich flavor and deep yellow-orange color. The seasoning is an important ingredient in Indian curries. It is also used to add color to foods such as butter, margarine, cheese, and mustard; to tint cotton, silk, paper, wood, and cosmetics; as a food preservative; and to make pickles.

What is the evidence?

Curcumin, an active ingredient in turmeric, is an antioxidant. Antioxidants are compounds that can protect the body's cells from damage caused by activated oxygen molecules known as free radicals. Laboratory studies have also shown that curcumin interferes with several important molecular pathways involved in cancer development, growth, and spread.

Recently, curcumin has received a great deal more attention in studies than turmeric as a whole herb. Researchers are studying curcumin to learn whether it is an effective anti-inflammatory agent and whether it holds any promise for cancer prevention or treatment. A number of studies of curcumin have shown promising results. Curcumin can kill cancer cells in laboratory dishes and also reduces growth of surviving cells. Curcumin also has been found to reduce development of several forms of cancer in laboratory animals and to shrink animal tumors.

Human studies of curcumin in cancer prevention and treatment are in the very early stages. One study of 15 patients with colorectal cancer was done to find out how much curcumin they could safely take, and whether they could take a dose large enough to be detected in the blood. The patients were able to take 3.6 grams of curcumin without noting ill effects. At this high dose, some curcumin and its products were found in the blood. Lower doses may work for the stomach and intestine. Even though it does not absorb well into the body, it has been shown to absorb into the colon lining and into any cancerous tissue in the colon. The researchers recommended that the high dose be used when curcumin is tested for effects outside the intestine. Other small studies have found people were able to take up to 10 grams per day for a period of a few weeks without noting problems. Some researchers are currently working on ways to increase absorption of curcumin by combining it with other substances. Further clinical trials are needed to find out what role, if any, turmeric and curcumin may play in the prevention or treatment of cancer.

Curcumin is being studied to see whether it helps other diseases as well. One small study of curcumin and another antioxidant called quercetin was done in adults who had kidney transplants. Those who took the combination in high dosages had fewer transplant rejections than those who received lower doses or placebo. More studies are needed to find out whether this holds true. Curcumin may also promote the emptying of the gallbladder, but again, more studies are needed.

Early studies showed promise that curcumin could correct the problem of cystic fibrosis, but later studies have been inconsistent and often showed no effect. Curcumin also seemed to help prevent stomach ulcers in rodents, although there are not good studies in humans to recommend it for this use.

Early research has suggested that curcumin may help lower "bad" cholesterol, reduce inflammation, and help with arthritis symptoms, although more reliable human studies are still needed. Tests of curcumin in HIV disease have been mixed and have generally not shown it to be helpful. In studies of mice, curcumin appeared to help with blocking the plaques and proteins that cause problems in the brain during Alzheimer's disease.

Although laboratory and animal tests look very promising, careful study is needed to find out whether curcumin will be useful for treating these conditions in humans. It is important to remember that extracted compounds such as curcumin are not the same as the whole herb, and study results would not be likely to show the same effects.

Are there any possible problems or complications?

This product is sold as a dietary supplement in the United States. Unlike companies that produce drugs (which must provide the FDA with results of detailed testing showing their product is safe and effective before the drug is approved for sale), the companies that make supplements do not have to show evidence of safety or health benefits to the FDA before selling their products. Supplement products without any reliable scientific evidence of health benefits may still be sold as long as the companies selling them do not claim the supplements can prevent, treat, or cure any specific disease. Some such products may not contain the amount of the herb or substance that is written on the label, and some may include other substances (contaminants). Though the FDA has written new rules to improve the quality of manufacturing processes for dietary supplements and the accurate listing of supplement ingredients, these rules do not take full effect until 2010. And, the new rules do not address the safety of supplement ingredients or their effects on health when proper manufacturing techniques are used.

Most such supplements have not been tested to find out if they interact with medicines, foods, or other herbs and supplements. Even though some reports of interactions and harmful effects may be published, full studies of interactions and effects are not often available. Because of these limitations, any information on ill effects and interactions below should be considered incomplete.

When used as a spice in foods, turmeric is considered safe. More research is needed to establish the safety of turmeric when used in herbal remedies. Little is known about the potential risks of taking the larger amounts used to treat illnesses. Taking large amounts by mouth may result in stomach pain, gas, indigestion, and nausea. Skin rash and stomach ulcers have been reported after long-term use, and allergic reactions are possible. People who are allergic to ginger or yellow food colorings are more likely to be allergic to turmeric.

A recent safety study in humans suggested that curcumin changes metabolism of oxalate, a substance that can form kidney stones. The researchers urged caution in use of this supplement by people with other conditions that make them susceptible to kidney stones.

People taking blood-thinning medications, drugs that suppress the immune system, or non-steroidal pain relievers (such as ibuprofen) should avoid turmeric because of the risk of harmful drug interactions. In animal and laboratory studies, turmeric made certain anti-cancer drugs less effective. Antioxidant supplements can interfere with the effectiveness of chemotherapy or radiation treatment. Patients who are in cancer treatment should talk to their doctor before taking vitamins, minerals, or other supplements.

In addition, other potential interactions between turmeric and other drugs and herbs should be considered. Always tell your doctor and pharmacist about any herbs or supplements you are taking.

People with bleeding disorders, obstructions of the bile duct, or a history of ulcers also should avoid turmeric. Women who are pregnant or breast-feeding should not use this herb. The amount of turmeric found in foods is thought to be safe for those who are not allergic to it. Applying turmeric to the skin for long periods of time can cause a yellow discoloration of the skin that may be difficult to remove.

Relying on this type of treatment alone and avoiding or delaying conventional medical care for cancer may have serious health consequences.

Additional Resources

More information from your American Cancer Society

The following information on complementary and alternative therapies may also be helpful to you. These materials may be found on our Web site ( or ordered from our toll-free number (1-800-ACS-2345).

Guidelines for Using Complementary and Alternative Methods
How to Know What Is Safe: Choosing and Using Dietary Supplements
The ACS Operational Statement on Complementary and Alternative Methods of Cancer Management
Complementary and Alternative Methods for Cancer Management
Placebo Effect
Learning About New Ways to Treat Cancer
Learning About New Ways to Prevent Cancer

Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003;23:363-398.

Aggarwal BB, Shishodia S, Takada Y, Banjerjee S, Newman RA, Bueso-Ramos CE, Price JE. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin Cancer Res. 2005;11:7490-7498.

Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007;4:807-818.

Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin, TX: American Botanical Council; 1998.

Deshpande SS, Ingle AD, Maru GB. Inhibitory effects of curcumin-free aqueous turmeric extract on benzo[a]pyrene-induced forestomach papillomas in mice. Cancer Lett. 1997;118:79-85.

Egan ME, Pearson M, Weiner SA, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects. Science. 2004;304:600-602.

Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. Springhouse, PA: Springhouse Corp; 1999.

Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol Biomarkers Prev. 2005;14:120-125.

Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol. 2008;75:787-809.

Grubb BR, Gabriel SE, Mengos A, Gentzsch M, Randell SH, Van Heeckeren AM, Knowles MR, Drumm ML, Riordan JR, Boucher RC. SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis. Am J Respir Cell Mol Biol. 2006;34:355-363.

Gruenwald J. PDR for Herbal Medicines. 3rd ed. Montvale, NJ: Thomson PDR; 2004.

Hastak K, Lubri N, Jakhi SD, More C, John A, Ghaisas SD, Bhide SV. Effect of turmeric oil and turmeric oleoresin on cytogenetic damage in patients suffering from oral submucous fibrosis. Cancer Lett. 1997:116:265-269.

Kim DC, Kim SH, Choi BH, Baek NI, Kim D, Kim MJ, Kim KT. Curcuma longa extract protects against gastric ulcers by blocking H2 histamine receptors. Biol Pharm Bull. 2005;28:2220-2224.

Kunnumakkara AB, Diagaradjane P, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S. Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products. Clin Cancer Res. 2008;14:2128-2136.

Lawenda BD, Kelly KM, Ladas EJ, Sagar SM, Vickers A, Blumberg JB. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? J Natl Cancer Inst. 2008;100:773-783.

Lin YG, Kunnumakkara AB, Nair A, Merritt WM, Han LY, Armaiz-Pena GN, Kamat AA, Spannuth WA, Gershenson DM, Lutgendorf SK, Aggarwal BB, Sood AK. Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Clin Cancer Res. 2007;13:3423-3430.

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Rafatullah S, Tariq M, Al-Yahya MA, Mossa JS, Ageel AM. Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats. J Ethnopharmacol. 1990;29:25-34.

Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, Marczylo TH, Morgan B, Hemingway D, Plummer SM, Pirmohamed M, Gescher AJ, Steward WP. Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res. 2004;10:6847-6854.

Shoskes D, Lapierre C, Cruz-Corerra M, Muruve N, Rosario R, Fromkin B, Braun M, Copley J. Beneficial effects of the bioflavonoids curcumin and quercetin on early function in cadaveric renal transplantation: a randomized placebo controlled trial. Transplantation. 2005;80:1556-1559.

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Note: This information may not cover all possible claims, uses, actions, precautions, side effects or interactions. It is not intended as medical advice, and should not be relied upon as a substitute for consultation with your doctor, who is familiar with your medical situation.

Last Medical Review: 11/01/2008
Last Revised: 11/01/2008

Susie xx

PostPosted: Sun Feb 28, 2010 5:54 am 
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Joined: Tue Apr 29, 2008 2:32 am
Posts: 3270
Location: New York
Hey there:

I don't think this is noted here, but I may have missed it.

Was reading on tonight and stumbled across an article there about curcumin and arthritis: ... 043&src=VW

To study the effect of curcumin on cartilage breakdown in vitro (in the laboratory), a research team from the University of Nottingham established a model of cartilage inflammation that mimics the inflammatory events thought to occur in osteoarthritis.

Here's the academic abstract:

Gotta go take mine now... :yes:


"Ours is the portal of hope. Come as you are." -- Rumi

PostPosted: Mon Mar 01, 2010 2:41 am 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
Always worth repeating, yes it's bottom of page 1 here but without the link, so big help.
Cartilage repair has to be one of the toughies, and even invitro stage I think this is magic.
I hope it saves some sharks from persecution.

Daniel has not even a sign of the growth/sarcoid on his tummy which grew to 2 inches long.
He had turmeric in his feeds and a topical coating of turmeric powder mixed with a tiny amount of oil and a squirt of iodine solution used for lambs navels. It dried, and disappeared over a four week period and so far no sign of a return.
Biting flies carry Bovine Papilloma Virus (Spelling might be wrong), this can cause growths but if any more appear this Summer I shall not panic.

After a year of taking Turmeric daily myself, having started by finding it and adding to laminitis prone Ben's feeds, I keep saying thank you to 'God', Creator,Universe,Provider for helping me to maintain mobility and enjoy life, without constantly whining about my arthritis.
Susie xx

Pub Med link is and

Susie xx

Last edited by PiePony on Fri Dec 23, 2011 1:53 am, edited 1 time in total.

PostPosted: Tue Mar 02, 2010 1:21 pm 
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Joined: Mon Mar 02, 2009 6:44 pm
Posts: 215
Location: South Africa
I have bought about 400g from the local shop. I am hoping to be able to find a supplier soon for fresher Tumeric.

Schatzi is on a MSM, Glucosamine, Chondroitin supplement right now. And another one waiting in the wings for when that is finished. So far there has been no significant improvement. So I am going to start the Tumeric today and see how she goes.

I might even start to take it myself. My ankles tend to stiffen if I am immobile for too long and especially in the AM.

I have even told my mother and step father about this and am going to copy paste some of the information in here about the Tumeric and Curcuma in an email to her. They both suffer from arthritis. If it works for Schatzi and I, I will probably tell my other family members who suffer as well. Whether they take my advice or not remains to be seen LOL

As far as I read, 3 teaspoons once a day in feed should suffice? I will start with this dosage and adjust depending on how Shatzi responds :D

Thank you for all the information contained here about this!

The best views can be seen from the back of a horse.

PostPosted: Sun May 09, 2010 2:23 pm 
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Joined: Wed Oct 22, 2008 11:56 am
Posts: 206
Very interesting :)

I used turmeric for my horse some years ago - because someone told me it was a good thing to use to "strengthen" the liver and the hoofs.
I gave him only 1 tablespoon, and after a while he didn't want to eat his food, because of the turmeric. I tried putting water in the food (alfalfa + vitamins) to get it well mixed - but he really didn't like it.
Maybe I should try again?

Am I the only one with a horse who don't like turmeric? :huh:

PostPosted: Sun May 09, 2010 8:21 pm 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
Horse does not like the taste of turmeric? I mix my turmeric in a little soaked sugar beet which is very good for my laminitic prone pony offering fibre and sweetness without the fructans of grass. (I do of course avoid all ready mixed feeds which may have barley or molasses added.)

Have a look back to page 1 of this topic, at the bottom of the page:
From The
Osteoarthritis: Turmeric Spice Might Provide Natural Remedy
by: Stacey Oke, DVM, MSc
October 13 2009, Article # 15043

Curcumin, an extract of the spice turmeric, is a natural product with potent anti-inflammatory properties that also exerts beneficial effects on cartilage metabolism. Scientists believe curcumin inhibits degradative enzymes such as metalloproteinases and cyclooxygenase-2 (COX-2) and reduces cartilage cell apoptosis (programmed cell death).

I will not repeat all of the already pasted information, but there is evidence of help for cartilage damage at this early in vitro stage of research using turmeric.

I have previously taken Glucosamine & Chondroitin with no noticeable improvements to my pain relief or mobility having maintained the course for more than 4 months.
I did however notice improvemnt within 2 weeks of beginning a loading daily dose of turmeric.

MSM in conjunction with turmeric will help as it is sulphur which allows the body to uptake the benefits, since horses cannot eat onions MSM or flowers of sulphur, perhaps half a teaspoon to a tablespoon of turmeric would be a starting ratio?

Susie xx

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