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PostPosted: Thu Oct 15, 2009 9:42 pm 

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Location: UK Worcester/Hereford border
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Magic spice for prevention ( and cure) of most diseases.
Cup of water into saucepan. Add teaspoon of turmeric (for yourself or a tablespoon for your horse.). Add a few grinds of black pepper. Low heat, bring to boil and simmer for 7 to 10 minutes, add more water as required to save excessive thickening.
Add a couple of teaspoons of olive oil or coconut oil. Add a teaspoon of honey.
(Make larger quantity and when cool store in glass jars because plastics leech, pop into refrigerator and paste will keep for a week, and then divide paste later when making drinks, or to keep in feedstore and add paste to feeds.)
For horses, a tablespoon, twice daily. Itch, sarcoid,arthritis, laminitis, general health, most diseases. e.g.Turmeric kills throat cancer cells within 24 hours, a computer search of turmeric and throat cancer will bring up the relevant studies.

For humans and dogs:Top up with whole organic milk.Warm without boiling.

Add turmeric to stir fries or everything else when cooking.

Turmeric is fat soluble, so avoid processed and GMO oils, look for High Omega 3, best are olive oil, coconut oil and linseed/flax. Piperine in pepper adds to bioavailability.

http://www.ncbi.nlm.nih.gov/pubmed/ type in turmeric and name of disease.
Do a computer search like Google with turmeric and influenza, or heart disease, or cancer, diabetes, obesity etc.etc.

Turmeric root or powder has many compounds besides curcumin, these combine to provide a powerful synergistic effect, so often very much more effective than capsules.


Turmeric’s Beneficial Effects in a Nutshell

Strengthens and improves digestion

Reduces gas and bloating
Assists in the digestion of protein and with rice and bean dishes
Improves your body's ability to digest fats
Promotes proper metabolism, correcting both excesses and deficiencies
Maintains and improves intestinal flora
Improves elimination of wastes and toxins
Supports healthy liver function and detox

Turmeric helps increase bile flow making it a liver cleanser that can rejuvenate your liver cells and recharge their capability to break down toxins
Helps to prevent alcohol and other toxins from being converted into compounds that may be harmful to your liver
Supports formation of healthy tissue
Purifies your blood

Stimulates formation of new blood tissue
Anti-inflammatory: Helps to reduce irritation to tissues characterized by pain, redness, swelling and heat
Contains curcuminoids that fight cancer, arthritis, and Alzheimer’s

Curcuminoids are potent phytonutrients (plant-based nutrients) that contain powerful antioxidant properties
Counteract the damaging effects of free radicals in your body
Relieve arthritis pain and stiffness, anti-inflammatory agent
Anti-carcinogenic: “Curcumin has been shown to prevent a large of number of cancers in animal studies. Laboratory data indicate that curcumin can inhibit tumor initiation, promotion, invasion, angiogenesis and metastasis.”[1]
Supports treatment of Alzheimer’s disease: “Because Alzheimer's disease is caused in part by amyloid-induced inflammation, curcumin has been shown to be effective against Alzheimer's. Clinical trials are in progress at UCLA with curcumin for Alzheimer's.”[2]
Curcumin: Turmeric’s Active Anti-Inflammatory “Ingredient”

Most notably turmeric is known for its potent anti-inflammatory properties, which come from curcumin -- the pigment that gives turmeric its yellow-orange color, and which is thought to be responsible for many of its medicinal effects. There are an estimated three to five grams of curcumin in 100 grams of turmeric.

Curcumin has been shown to influence more than 700 genes, and it can inhibit both the activity and the synthesis of cyclooxygenase-2 (COX2) and 5-lipooxygenase (5-LOX), as well as other enzymes that have been implicated in inflammation.[3]

Turmeric’s Cancer-Fighting Properties

In India where turmeric is widely used, the prevalence of four common U.S. cancers -- colon, breast, prostate and lung -- is 10 times lower. In fact, prostate cancer, which is the most frequently diagnosed cancer in U.S. men, is rare in India and this is attributed, in part, to turmeric.

Numerous studies have looked into this potential cancer-fighting link, with promising results. For instance, curcumin has been found to:

Inhibit the proliferation of tumor cells
Inhibit the transformation of cells from normal to tumor
Help your body destroy mutated cancer cells so they cannot spread throughout your body
Decrease inflammation
Enhance liver function
Inhibit the synthesis of a protein thought to be instrumental in tumor formation
Prevent the development of additional blood supply necessary for cancer cell growth
As for the results of research studies, a study in Biochemical Pharmacology found that curcumin can slow the spread of breast cancer cells to the lungs in mice.[4]

"Curcumin acts against transcription factors, which are like a master switch," said lead researcher, Bharat Aggarwal. "Transcription factors regulate all the genes needed for tumors to form. When we turn them off, we shut down some genes that are involved in the growth and invasion of cancer cells."

A second study in Biochemical Pharmacology also found that curcumin inhibits the activation of NF-kappaB, a regulatory molecule that signals genes to produce a slew of inflammatory molecules (including TNF, COX-2 and IL-6) that promote cancer cell growth.[5]

Turmeric’s Essential Role for Your Liver

Your liver’s primary role is to process and remove toxins carried in your bloodstream. When functioning at its peak, it can filter up to two liters of blood per minute and easily break apart toxic molecules to reduce their toxicity. Your liver is also a crucial part of vitamin, mineral, protein, fat, carbohydrate and hormonal metabolism.

However, poor diet, allergens, pollution and stress can cause your liver to become sluggish, and this can impair its vital functions. This is where turmeric can be a very useful part of your liver support system. Studies have shown that it:

May increase important detoxification enzymes in your liver
Induces the formation of a primary liver detoxification enzyme, glutathione S-transferase (GST) enzymes
Turmeric is also a natural cholagogue, a medicinal agent that promotes the discharge of bile from your system. Increased bile flow is important to help your liver detoxify and to help your body digest fats.

Turmeric for Your Heart, Brain and Overall Health

Turmeric inhibits free radical damage of fats, including cholesterol. When cholesterol is damaged in this way, or oxidized, it can then damage your blood vessels and lead to a heart attack or stroke. Therefore, research suggests that turmeric’s ability to prevent the oxidation of cholesterol may be beneficial for your heart. It’s also rich in vitamin B6, high intakes of which are associated with a reduced risk of heart disease.

Meanwhile, turmeric appears to be highly protective against neurodegenerative diseases. In fact, in India levels of neurological diseases such as Alzheimer’s are very low, and studies have shown that curcumin can slow the progression of Alzheimer’s in mice. The compound has also proven capable of blocking the progression of multiple sclerosis.

Further, Professor Moolky Nagabhushan from the Loyola University Medical Center, Chicago, IL, who has been studying turmeric for the last 20 years, believes that turmeric can protect against harmful environmental chemicals, and in so doing protect against childhood leukemia. The research showed that curcumin in turmeric can:[7]

Inhibit the toxicity of polycyclic aromatic hydrocarbons (PAHs) (cancer-causing chemicals in the environment)
Inhibit radiation-induced chromosome damage
Prevent the formation of harmful heterocyclic amines and nitroso compounds, which may result in the body when eating certain processed foods, such as processed meat products
Irreversibly inhibit the multiplication of leukemia cells in a cell culture
Turmeric's volatile oils also have external anti-bacterial action. As such, they may help prevent bacterial wound infections and accelerate wound healing. Johnson & Johnson even sells a curcumin-containing Band-Aid in India!

And the therapeutic potential of turmeric and curcumin do not end there. Evidence suggests the spice may also be beneficial for:

Cystic fibrosis
Type 2 diabetes
Crohn’s disease
Psoriasis
Rheumatoid arthritis
Cataracts
Gallstones
Muscle regeneration
Inflammatory bowel disease

[1] The University of Texas MD Anderson Cancer Center, Complementary/Integrative Medicine Education Resources, “Curcumin at M.D. Anderson” (accessed January 22, 2009)

[2] The University of Texas MD Anderson Cancer Center, Complementary/Integrative Medicine Education Resources, “Curcumin at M.D. Anderson” (accessed January 22, 2009)

[3] The University of Texas MD Anderson Cancer Center, Complementary/Integrative Medicine Education Resources, “Curcumin at M.D. Anderson” (accessed January 22, 2009)

[4] Biochemical Pharmacology, Volume 70, Issue 5, 1 September 2005, Pages 700-713

[5] The World’s Healthiest Foods, Turmeric

[6] The World’s Healthiest Foods, Turmeric

[7] The World’s Healthiest Foods, Turmeric









Turmeric
Turmeric has a peppery, warm and bitter flavor and a mild fragrance slightly reminiscent of orange and ginger, and while it is best known as one of the ingredients used to make curry, it also gives mustard its bright yellow color.
Turmeric comes from the root of the Curcuma longa plant and has a tough brown skin and a deep orange flesh. Turmeric has long been used as a powerful anti-inflammatory in both the Chinese and Indian systems of medicine. Turmeric was traditionally called Indian saffron because of its deep yellow-orange color and has been used throughout history as a condiment, healing remedy and textile dye.
Safety

Turmeric is not a commonly allergenic food and is not known to contain measurable amounts of goitrogens, oxalates, or purines.

Nutritional Profile

Turmeric is an excellent source of both iron and manganese. It is also a good source of vitamin B6, dietary fiber and potassium.

History

Turmeric is native to Indonesia and southern India, where it has been harvested for more than 5,000 years. It has served an important role in many traditional cultures throughout the East, including being a revered member of the Ayurvedic pharmacopeia. While Arab traders introduced it into Europe in the 13th century, it has only recently become popular in Western cultures. Much of its recent popularity is owed to the recent research that has highlighted its therapeutic properties. The leading commercial producers of turmeric include India, Indonesia, China, the Philippines, Taiwan, Haiti and Jamaica.


Health Benefits

Turmeric (Curcuma longa), the bright yellow of the spice rainbow, is a powerful medicine that has long been used in the Chinese and Indian systems of medicine as an anti-inflammatory agent to treat a wide variety of conditions, including flatulence, jaundice, menstrual difficulties, bloody urine, hemorrhage, toothache, bruises, chest pain, and colic.

A Potent, Yet Safe Anti-Inflammatory

The volatile oil fraction of turmeric has demonstrated significant anti-inflammatory activity in a variety of experimental models. Even more potent than its volatile oil is the yellow or orange pigment of turmeric, which is called curcumin. Curcumin is thought to be the primary pharmacological agent in turmeric. In numerous studies, curcumin's anti-inflammatory effects have been shown to be comparable to the potent drugs hydrocortisone and phenylbutazone as well as over-the-counter anti-inflammatory agents. Unlike the drugs, which are associated with significant toxic effects (ulcer formation, decreased white blood cell count, intestinal bleeding), curcumin produces no toxicity.

An Effective Treatment for Inflammatory Bowel Disease

Curcumin may provide an inexpensive, well-tolerated, and effective treatment for inflammatory bowel disease (IBD) such as Crohn's and ulcerative colitis, recent research suggests. In this study, mice given an inflammatory agent that normally induces colitis were protected when curcumin was added to their diet five days beforehand. The mice receiving curcumin not only lost much less weight than the control animals, but when researchers checked their intestinal cell function, all the signs typical of colitis (mucosal ulceration, thickening of the intestinal wall, and the infiltration of inflammatory cells)were all much reduced. While the researchers are not yet sure exactly how curcumin achieves its protective effects, they think its benefits are the result of not only antioxidant activity, but also inhibition of a major cellular inflammatory agent called NF kappa-B. Plus, an important part of the good news reported in this study is the fact that although curcumin has been found to be safe at very large doses, this component of turmeric was effective at a concentration as low as 0.25 per cent-an amount easily supplied by simply enjoying turmeric in flavorful curries.
Relief for Rheumatoid Arthritis

Clinical studies have substantiated that curcumin also exerts very powerful antioxidant effects. As an antioxidant, curcumin is able to neutralize free radicals, chemicals that can travel through the body and cause great amounts of damage to healthy cells and cell membranes. This is important in many diseases, such as arthritis, where free radicals are responsible for the painful joint inflammation and eventual damage to the joints. Turmeric's combination of antioxidant and anti-inflammatory effects explains why many people with joint disease find relief when they use the spice regularly. In a recent study of patients with rheumatoid arthritis, curcumin was compared to phenylbutazone and produced comparable improvements in shortened duration of morning stiffness, lengthened walking time, and reduced joint swelling.

Help for Cystic Fibrosis Sufferers

Curcumin, the major constituent of turmeric that gives the spice its yellow color, can correct the most common expression of the genetic defect that is responsible for cystic fibrosis, suggests an animal study published in the Science (April 2004). Cystic fibrosis, a fatal disease that attacks the lungs with a thick mucus, causing life-threatening infections, afflicts about 30,000 American children and young adults, who rarely survive beyond 30 years of age. The mucus also damages the pancreas, thus interfering with the body-ability to digest and absorb nutrients.

Researchers now know that cystic fibrosis is caused by mutations in the gene that encodes for a protein (the transmembrane conductance regulator or CFTR). The CTFR protein is responsible for traveling to the cell-surface and creating channels through which chloride ions can leave the cell. When the protein is abnormally shaped because of a faulty gene, this cannot happen, so chloride builds up in the cells, which in turn, leads to mucus production.

The most common mutation, which is called DeltaF508, results in the production of a misfolded protein. When mice with this DeltaF508 defect were given curcumin in doses that, on a weight-per-weight basis, would be well-tolerated by humans, curcumin corrected this defect, resulting in a DeltaF508 protein with normal appearance and function. In addition, the Yale scientists studying curcumin have shown that it can inhibit the release of calcium, thus allowing mutated CTFR to exit cells via the calcium channels, which also helps stop the chloride-driven build up of mucus. Specialists in the treatment of cystic fibrosis caution, however, that patients should not self-medicate with dietary supplements containing curcumin, until the correct doses are known and any adverse interactions identified with the numerous prescription drugs taken by cystic fibrosis sufferers.

Cancer Prevention

Curcumin's antioxidant actions enable it to protect the colon cells from free radicals that can damage cellular DNA—a significant benefit particularly in the colon where cell turnover is quite rapid, occuring approximately every three days. Because of their frequent replication, mutations in the DNA of colon cells can result in the formation of cancerous cells much more quickly. Curcumin also helps the body to destroy mutated cancer cells, so they cannot spread through the body and cause more harm. A primary way in which curcumin does so is by enhancing liver function. Additionally, other suggested mechanisms by which it may protect against cancer development include inhibiting the synthesis of a protein thought to be instrumental in tumor formation and preventing the development of additional blood supply necessary for cancer cell growth.

Inhibits Cancer Cell Growth and Metastases

Epidemiological studies have linked the frequent use of turmeric to lower rates of breast, prostate, lung and colon cancer; laboratory experiments have shown curcumin can prevent tumors from forming; and research conducted at the University of Texas suggests that even when breast cancer is already present, curcumin can help slow the spread of breast cancer cells to the lungs in mice.

In this study, published in Biochemical Pharmacology (September 2005), human breast cancer cells were injected into mice, and the resulting tumors removed to simulate a mastectomy.

The mice were then divided into four groups. One group received no further treatment and served as a control. A second group was given the cancer drug paclitaxel (Taxol); the third got curcumin, and the fourth was given both Taxol and curcumin.

After five weeks, only half the mice in the curcumin-only group and just 22% of those in the curcumin plus Taxol group had evidence of breast cancer that had spread to the lungs.

But 75% of the mice that got Taxol alone and 95% of the control group developed lung tumours.

How did curcumin help? "Curcumin acts against transcription factors, which are like a master switch," said lead researcher, Bharat Aggarwal. "Transcription factors regulate all the genes needed for tumors to form. When we turn them off, we shut down some genes that are involved in the growth and invasion of cancer cells."

In another laboratory study of human non-Hodgkin's lymphoma cells published in Biochemical Pharmacology (September 2005), University of Texas researchers showed that curcumin inhibits the activation of NF-kappaB, a regulatory molecule that signals genes to produce a slew of inflammatory molecules (including TNF, COX-2 and IL-6) that promote cancer cell growth. In addition, curcumin was found to suppress cancer cell proliferation and to induce cell cycle arrest and apoptosis (cell suicide) in the lung cancer cells. Early phase I clinical trials at the University of Texas are now also looking into curcumin's chemopreventive and therapeutic properties against multiple myeloma and pancreatic cancer, and other research groups are investigating curcumin's ability to prevent oral cancer.

Turmeric and Onions May Help Prevent Colon Cancer

Curcumin, a phytonutrient found in the curry spice turmeric, and quercitin, an antioxidant in onions, reduce both the size and number of precancerous lesions in the human intestinal tract, shows research published in the August 2006 issue of Clinical Gasteroenterology and Hepatology.

Five patients with an inherited form of precancerous polyps in the lower bowel known as familial adenomatous polyposis (FAP) were treated with regular doses of curcumin and quercetin over an average of six months. The average number of polyps dropped 60.4%, and the average size of the polyps that did develop dropped by 50.9%.

FAP runs in families and is characterized by the development of hundreds of polyps (colorectal adenomas) and, eventually, colon cancer. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs such as aspirin, ibuprofen) have been used to treat some patients with this condition, but these drugs often produce significant side effects, including gastrointestinal ulcerations and bleeding, according to lead researcher Francis M. Giardiello, M.D., at the Division of Gastroenterology, Johns Hopkins University.

Previous observational studies in populations that consume large amounts of curry, as well as animal research, have strongly suggested that curcumin, one of the main ingredients in Asian curries, might be effective in preventing and/or treating cancer in the lower intestine. Similarly, quercetin, an anti-oxidant flavonoid found in a variety of foods including onions, green tea and red wine, has been shown to inhibit growth of colon cancer cell lines in humans and abnormal colorectal cells in animals.

In this study, a decrease in polyp number was observed in four of five patients at three months and four of four patients at six months.

Each patient received curcumin (480 mg) and quercetin (20 mg) orally 3 times a day for 6 months. Although the amount of quercetin was similar to what many people consume daily, the curcumin consumed was more than would be provided in a typical diet because turmeric only contains on average 3-5 % curcumin by weight.

While simply consuming curry and onions may not have as dramatic an effect as was produced in this study, this research clearly demonstrates that liberal use of turmeric and onions can play a protective role against the development of colorectal cancer. And turmeric doesn't have to only be used in curries. This spice is delicious on healthy sautéed apples, and healthy steamed cauliflower and/or green beans and onions. Or, for a flavor-rich, low-calorie dip, try adding some turmeric and dried onion to creamy yogurt.

Turmeric Teams Up with Cauliflower to Halt Prostate Cancer

Prostate cancer—the second leading cause of cancer death in American men with 500,000 new cases appearing each year—is a rare occurrence among men in India, whose low risk is attributed to a diet rich in brassica family vegetables and the curry spice, turmeric.

Scientists tested turmeric, a concentrated source of the phytonutrient curcumin, along with phenethyl isothiocyanates, a phytochemical abundant in cruciferous vegetables including cauliflower, cabbage, broccoli, Brussels sprouts, kale, kohlrabi and turnips.

When tested singly, both phenethyl isothiocyanate and curcumin greatly retarded the growth of human prostate cancer cells implanted in immune-deficient mice. In mice with well-established prostate cancer tumors, neither phenethyl isothiocyanate nor curcumin by itself had a protective effect, but when combined, they significantly reduced both tumor growth and the ability of the prostate cancer cells to spread (metastasize) in the test animals.

The researchers believe the combination of cruciferous vegetables and curcumin could be an effective therapy not only to prevent prostate cancer, but to inhibit the spread of established prostate cancers. Best of all, this combination-cauliflower spiced with turmeric-is absolutely delicious! For protection against prostate cancer, cut cauliflower florets in quarters and let sit for 5-10 minutes; this allows time for the production of phenethyl isothiocyanates, which form when cruciferous vegetables are cut, but stops when they are heated. Then sprinkle with turmeric, and healthy sauté on medium heat in a few tablespoons of vegetable or chicken broth for 5 minutes. Remove from the heat and top with olive oil, sea salt and pepper to taste.

Reduce Risk of Childhood Leukemia

Research presented at a recent conference on childhood leukemia, held in London, provides evidence that eating foods spiced with turmeric could reduce the risk of developing childhood leukemia. The incidence of this cancer has risen dramatically during the 20th century, mainly in children under age five, among whom the risk has increased by more than 50% cent since 1950 alone. Modern environmental and lifestyle factors are thought to play a major role in this increase.

Childhood leukemia is much lower in Asia than Western countries, which may be due to differences in diet, one of which, the frequent use of turmeric, has been investigated in a series of studies over the last 20 years by Prof. Moolky Nagabhushan from the Loyola University Medical Centre, Chicago, IL.

"Some of the known risk factors that contribute to the high incidence of childhood leukemia are the interaction of many lifestyle and environmental factors. These include prenatal or postnatal exposure to radiation, benzene, environmental pollutants and alkylating chemotherapeutic drugs. Our studies show that turmeric-and its colouring principle, curcumin-in the diet mitigate the effects of some of these risk factors."

Nagabhushan has shown that the curcumin in turmeric can:

inhibit the mutagenicity of polycyclic aromatic hydrocarbons (PAHs) (carcinogenic chemicals created by the burning of carbon based fuels including cigarette smoke)
inhibit radiation-induced chromosome damage
prevent the formation of harmful heterocyclic amines and nitroso compounds, which may result in the body when certain processed foods, such as processed meat products that contain nitrosamines, are eaten
irreversibly inhibit the multiplication of leukemia cells in a cell culture
Improved Liver Function

In a recent rat study conducted to evaluate the effects of turmeric on the liver's ability to detoxify xenobiotic (toxic) chemicals, levels of two very important liver detoxification enzymes (UDP glucuronyl transferase and glutathione-S-transferase) were significantly elevated in rats fed turmeric as compared to controls. The researchers commented, "The results suggest that turmeric may increase detoxification systems in addition to its anti-oxidant properties...Turmeric used widely as a spice would probably mitigate the effects of several dietary carcinogens."

Curcumin has been shown to prevent colon cancer in rodent studies. When researchers set up a study to analyze how curcumin works, they found that it inhibits free radical damage of fats (such as those found in cell membranes and cholesterol), prevents the formation of the inflammatory chemical cyclooxygenase-2 (COX-2), and induces the formation of a primary liver detoxification enzyme, glutathione S-transferase (GST) enzymes. When the rats were given curcumin for 14 days, their livers' production of GST increased by 16%, and a marker of free radical damage called malondialdehyde decreased by 36% when compared with controls. During this two week period, the researchers gave the rats a cancer-causing chemical called carbon tetrachloride. In the rats not fed curcumin, markers of free radical damage to colon cells went up, but in the rats given turmeric, this increase was prevented by dietary curcumin. Lastly, the researchers compared giving turmeric in the diet versus injecting curcumin into the rats' colons. They found injecting curcumin resulted in more curcumin in the blood, but much less in the colon mucosa. They concluded, "The results show that curcumin mixed with the diet achieves drug levels in the colon and liver sufficient to explain the pharmacological activities observed and suggest that this mode of administration may be preferable for the chemoprevention of colon cancer."

Cardiovascular Protection

Curcumin may be able to prevent the oxidation of cholesterol in the body. Since oxidized cholesterol is what damages blood vessels and builds up in the plaques that can lead to heart attack or stroke, preventing the oxidation of new cholesterol may help to reduce the progression of atherosclerosis and diabetic heart disease. In addition, turmeric is a good source of vitamin B6, which is needed to keep homocysteine levels from getting too high. Homocysteine, an intermediate product of an important cellular process called methylation, is directly damaging to blood vessel walls. High levels of homocysteine are considered a significant risk factor for blood vessel damage, atherosclerotic plaque build-up, and heart disease; while a high intake of vitamin B6 is associated with a reduced risk of heart disease.

In research published in the Indian Journal of Physiology and Pharmacology, when 10 healthy volunteers consumed 500 mg of curcumin per day for 7 days, not only did their blood levels of oxidized cholesterol drop by 33%, but their total cholesterol droped 11.63% , and their HDL (good cholesterol) increased by 29%! (Soni KB, Kuttan R).
How Turmeric Lowers Cholesterol

Tumeric's cholesterol-lowering effects are the result of the curry spice's active constituent, curcumin, which research reveals is a messaging molecule that communicates with genes in liver cells, directing them to increase the production of mRNA (messenger proteins) that direct the creation of receptors for LDL (bad) cholesterol. With more LDL-receptors, liver cells are able to clear more LDL-cholesterol from the body.

LDL-receptor mRNA increased sevenfold in liver cells treated with curcumin at a concentration of 10 microM, compared to untreated cells. (Liver cells were found to tolerate curcumin at levels of up to 12. microM for 24 hours). (Peschel D, Koerting R, et al. J Nutr Biochem)

Practical Tips:

Help increase your liver's ability to clear LDL-cholesterol by relying on turmeric, not just for delicious fish, meat or lentil curries, but to spice up healthy sautéeed onions, potatoes and/or cauliflower; or as the key flavoring for a creamy vegetable dip. Just mix plain yogurt with a little omega-3-rich mayonnaise and turmeric, salt and pepper to taste. Serve with raw cauliflower, celery, sweet pepper, jicama and broccoli florets. Be sure to choose turmeric rather than prepared curry blends. Recent research indicates the amount of turmeric (and therefore curcumin) in curry blends is often minimal.(Tayyem RF et al.,Nutr Cancer)

For the most curcumin, be sure to use turmeric rather curry powder-a study analyzing curcumin content in 28 spice products described as turmeric or curry powders found that pure turmeric powder had the highest concentration of curcumin, averaging 3.14% by weight. The curry powder samples, with one exception, contained very small amounts of curcumin. (Tayyem RF, Heath DD, et al. Nutr Cancer)
Protection against Alzheimer's Disease

Growing evidence suggests that turmeric may afford protection against neurodegenerative diseases. Epidemiological studies show that in elderly Indian populations, among whose diet turmeric is a common spice, levels of neurological diseases such as Alzheimer's are very low. Concurrently, experimental research conducted recently found that curcumin does appear to slow the progression of Alzheimer's in mice. Preliminary studies in mice also suggest that curcumin may block the progression of multiple sclerosis. While it is still unclear how it may afford protection against this degenerative condition, one theory is that it may interrupt the production of IL-2, a protein that can play a key role in the destruction of myelin, the sheath that serves to protect most nerves in the body.

A number of studies have suggested that curcumin, the biologically active constituent in turmeric, protects against Alzheimer's disease by turning on a gene that codes for the production of antioxidant proteins. A study published in the Italian Journal of Biochemistry (December 2003) discussed curcumin's role in the induction of the the heme oxygenase pathway, a protective system that, when triggered in brain tissue, causes the production of the potent antioxidant bilirubin, which protects the brain against oxidative (free radical) injury. Such oxidation is thought to be a major factor in aging and to be responsible for neurodegenerative disorders including dementias like Alzheimer's disease. Another study conducted jointly by an Italian and U.S. team and presented at the American Physiological Society's 2004 annual conference in Washington, DC, confirmed that curcumin strongly induces expression of the gene, called hemeoxygenase-1 (HO-1) in astrocytes from the hippocampal region of the brain.

Curcumin Crosses Blood-Brain Barrier, May Help Prevent Alzheimer's Disease

Research conducted at UCLA and published in the Journal of Biological Chemistry (December 2004), which has been confirmed by further research published in the Journal of Agricultural and Food Chemistry (April 2006), provides insight into the mechanisms behind curcumin's protective effects against Alzheimer's disease.

Alzheimer's disease results when a protein fragment called amyloid¦Â accumulates in brain cells, producing oxidative stress and inflammation, and forming plaques between nerve cells (neurons) in the brain that disrupt brain function.

Amyloid is a general term for protein fragments that the body produces normally. Amyloid¦Â is a protein fragment snipped from another protein called amyloid precursor protein (APP). In a healthy brain, these protein fragments are broken down and eliminated. In Alzheimer's disease, the fragments accumulate, forming hard, insoluble plaques between brain cells.

The UCLA researchers first conducted test tube studies in which curcumin was shown to inhibit amyloid¦Â aggregation and to dissolve amyloid fibrils more effectively than the anti-inflammatory drugs ibuprofen and naproxen. Then, using live mice, the researchers found that curcumin crosses the blood brain barrier and binds to small amyloid- species. Once bound to curcumin, the amyloid- protein fragments can no longer clump together to form plaques. Curcumin not only binds to amyloid-Â, but also has anti-inflammatory and antioxidant properties, supplying additional protection to brain cells.

Turmeric Boosts Amyloid Plaque Clearance in Human Alzheimer's Patients

The most active ingredient in turmeric root, bisdemethoxycurcumin, boosts the activity of the immune system in Alzheimer's patients, helping them to clear the amyloid beta plaques characteristic of the disease.

In healthy patients, immune cells called macrophages, which engulf and destroy abnormal cells and suspected pathogens, efficiently clear amyloid beta, but macrophage activity is suppressed in Alzheimer's patients.

Using blood samples from Alzheimer's patients, Drs. Milan Fiala and John Cashman have shown that bisdemethoxycurcumin boosts macrophage activity to normal levels, helping to clear amyloid beta. Fiala and Cashman also observed that bisdemethoxycurcumin was more effective in promoting the clearance of amyloid beta in some patients' blood than others, hinting at a genetic element. Further study revealed the genes involved are MGAT III and Toll-like receptors, which are also responsible for a number of other key immune functions. Bisdemethoxycurcumin enhances the transcription of these genes, correcting the immune defects seen in Alzheimer's patients. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12849-54.



Source

The World’s Healthiest Foods: Turmeric

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Last edited by PiePony on Mon Dec 16, 2013 3:14 pm, edited 3 times in total.

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PostPosted: Fri Oct 16, 2009 9:34 am 
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Joined: Tue May 15, 2007 2:40 pm
Posts: 4733
Location: Belgium
Well, even if all the scientists in the world were against it, I am convinced for it worked on Owen already... and, I gave Jamie the curcuma for a week now... and the lumb on his belly is half the size!!! :ieks: He trots!

I am using it myself, I have more energy and more flexibility and endurance (I used to be dizzy a lot when running). And my tempers ( :twisted: ) seem to have gone down as well :)
Now I am giving it to all three horses, my dog Gina and 4 cats.

Maybe curcuma is going to be the AND wonder herb. :applause: Just a shame that it isn't fluorescent green.



[oh yes, and - just in case - a note for everybody who reads this; I personnaly am against animal testing at all times.]

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PostPosted: Fri Oct 16, 2009 12:58 pm 

Joined: Sat Mar 08, 2008 12:45 pm
Posts: 108
Location: UK
Hi Josepha,
What dose do you use for your various animals (and yourself :) )?
I may try it with my long-term lame horse...... he isn't getting any better :sad:.
Thanks.

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PostPosted: Fri Oct 16, 2009 2:27 pm 

Joined: Fri Nov 07, 2008 2:02 pm
Posts: 1072
Location: UK Worcester/Hereford border
Orangehoof, I used to take capsules until Nina told me that the powder was more directly beneficial. I mix a heaped teaspoon into a small amount of water morning and night, but sometimes I add two teaspoons into a big mug full of water and just enjoy the refreshment.
My horses have a little soaked beet daily which allows me to add their magnesium oxide, cinnamon and turmeric without causing sneezes and dust. They have approx 3 teaspoons a day each, but if Ben looks a little stiff he gets 3 teaspoons twice a day in a tiny feed with a teaspoon of cinnamon for his laminitis.
Nina prefers her turmeric with fruit juice. Whilst I really do not like curry, I love the taste of the turmeric, strange!
I buy in kilo packs from Ebay and search for best price including post and packing, usually I order 2 kilo's at a time.
The owner of my village post office and shop goes to the warehouse and can sometimes buy 380 gram chef packs of turmeric for around £3.50, so I ask him to collect 3 jars for me and horses to save waiting time on postage occaisionally.
I usually allow 3 months for my body to tell me if something is working, but within 9 days of changing from capsules to powder, I can honestly say I have not felt so good in the past few years with my arthritis.

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PostPosted: Fri Oct 16, 2009 2:40 pm 
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Does anyone know wether or not it is available somewhere in holland in not to large amounts (I don't have to feed an orphanage) ?

Sounds really really good!

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PostPosted: Fri Oct 16, 2009 2:46 pm 

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Location: UK
Thank you Susie :f:.

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PostPosted: Fri Oct 16, 2009 2:56 pm 

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Location: UK Worcester/Hereford border
KDS if you have some empty coffee jars you can use to store the powder, this is one on ebay Netherlands, that I have purchased in the UK.
http://cgi.ebay.nl/herbs-Spices-Turmeri ... 33530e0beb

and this is a smaller amount but I cannot read the p+p etc because I am useless at languages.
http://cgi.ebay.nl/KURKUMA-GEMAHLEN-HAL ... 1c0d23ca7b

UK Ebay shop do a search for turmeric but will supply almost any quantity
http://stores.shop.ebay.co.uk/The-Alchemists-Apothecary

I have just bought this book via Ebay:
http://cgi.ebay.co.uk/Turmeric-and-the- ... 35a42c27c0
ISBN 13: 9780879837686
ISBN 10: 0879837683
SKU: BNT-0879837683
Title: Turmeric and the Healing Curcuminoids (Keats Good Health Guide)
Author: Muhammed Majeed Vladimir Badmaev Frank Murray
Publisher: McGraw-Hill Contemporary
Media: Paperback
Pages: 48

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Last edited by PiePony on Fri Oct 16, 2009 3:41 pm, edited 2 times in total.

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PostPosted: Fri Oct 16, 2009 3:23 pm 
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I could sell it too, but have not put it in my (web) shop yet because of the codex alimantarius.

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PostPosted: Fri Oct 16, 2009 5:53 pm 
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Josepha wrote:
I could sell it too, but have not put it in my (web) shop yet because of the codex alimantarius.


Over zealous government is the plague of humankind, and other living creatures. While they protect they often destroy as well. Such wrong headedness.

Gosh, Josepha, don't you have a corner in your online shop where you have cooking items, books, utensils, dried cooking herbs, etc.? ;) :yes: :smile:

I love to cook. I cook all breakfast meals, one of my favorites of the day, and I never fail to dust my eggs with extra turmeric. Interestingly, long before I ever read of the health benefits attributed to this substance I craved it.

But then I've been like that most of my life. It seems I crave the things my body (and mind) need. I came back to horses, didn't it then? :funny:

I don't find parsley a very interesting flavor, yet every now and then I want a whole large sprig of it, and it seems to make my digestion better.

Is there an organization like our ACLU (American Civil Liberties Union) in your country or a European Union focused one? I'm thinking it's badly needed if not already present. I know when I heard the first rumblings about the idea of creating a European union it made my skin crawl, and I foresaw things just like this happening, and worse to come.

We have barely held the Tiger of big government at bay here in the U.S. but have a tradition, both from the founders of our present form of government, and written into our constitution, of "States Rights."

The whole mess is held together for the short time (relative to European history that is) it has precisely because it is a MESS. That is all the conflicting interests, and the efforts expended in their promotion and behalf of the the believers in those interests creates a nice network of tensions, rather like a Buckminster Fuller cable and canvas domed edifice, and it continues to stand. The winds can bend it and on occasion something will snap, but in the end it stands and we can repair it out of enlightened self interest.

You mentioned in a post today the particular quality or qualities of AND folks, and I agree most heartily with you ... it is the very kind of people we meet here on AND and are attracted to the AND philosophy that
are most likely to continue to repair the edifice of centralized government. Don't let the codex people win.

At the risk of offending (not that I've failed to in the past :roll: ) I'll point out that big government tends first to perpetuate itself and serve second, or often, serve at far lower priority than even second place to self preservation and perpetuation. The EU is rapidly approaching this, if I'm not mistaken, though you that are subject to it close up could better assess it's activities and their quality or lack of it in your lives.

All this over Turmeric. I do so hate intrusive government when they lack proof of harm. How many people have been injured or died from ingesting Turmeric I wonder. :funny: :funny: :funny: :funny:

And yes, here in the U.S. we have similar problems over nutritional supplements and herbal nostroms and substances. So we haven't completely mastered big government ourselves, but we work on it.

There have to be folks there of the same mind: curb big government before it swallows us.

We are fighting "chipping," our horses with an electronic chip that can be used as a locator device. Government actually wants to fine us if we refuse to have our animals, even little chickens, chipped. Weird, no? They'll be chipping us next if we let these kinds of things go by.

Donald, Nettlepatch Farm

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PostPosted: Fri Oct 16, 2009 8:01 pm 

Joined: Thu Feb 05, 2009 7:50 pm
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Location: Upstate New York, USA
I am so happy to say the least, finally people are listening and willing to try. I have been talking about the benefits of turmeric forever it feels like but nobody ever listened and was willing to give it a try. Forum after forum they just said 'yes, how nice' but that was all anybody ever had to say until Susie looked into it herself and was convinced this is something worth trying and see and hear, it works for her and the horses also. Finally, finally, finally no more deaf ears. I actually had gotten to the point of thinking if I should ever say anything again and somebody actually listened and tried. Now at least all my preaching was not in vain, hurray. Almost everything turmeric does, ginger can also do but try to get 30g a day into a horse! Mine don't like the smell of ginger never mind eating it.

What I forgot to say about the turmeric, the darker the orange the stronger the powder and also don't leave it in a plastic bag, it will eat through it. I put it in glass jars and away from heat and sunlight to keep it's potency.

I am so pleased I could burst. I am truly tickled pink!

Nina xx


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PostPosted: Fri Oct 16, 2009 8:54 pm 

Joined: Fri Nov 07, 2008 2:02 pm
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Location: UK Worcester/Hereford border
http://food-beverages.exportersindia.co ... rmeric.htm
http://www.indianyellowpages.com/food-b ... rmeric.htm
The above are googles for wholesale turmeric dealers. I am not sure about regulations because I am not a trader. I rather suspect that if Equihof is able to buy wholesale and sell in 500gm to 5 kilo packages, then Ralph will be good at sourcing from the best wholesale markets.

However, I suppose Donald mentioning cooking and herbs/spices for cooking, it could be less regulated than as a medicinal product.

This paragraph is an excerpt from turmeric-curcumin.com (who prefer to sell their capsule curcumin extract rather than have us buy powder)

Why hasn't the pharmaceutical industry patented Curcumin?

The global pharmaceutical corporations are very interested in owning patents for Curcumin and Turmeric because of the much heralded scientific evidence and the long history of its healing properties. However, that same evidence and history of Turmeric and Curcumin being used medicinally for centuries was the reason the United States Patent and Trademark Office rejected and revoked the patenting rights (Patent No. 5401504) of Turmeric on the grounds that the claims were not new: "USPTO unequivocally rejected all six claims made on August 13, 2001 ruling that Turmeric's medicinal properties were not patentable." As Dr. Bharat B. Aggarwal of the University of Texas MD Anderson Cancer Center in Houston explains: "in the case of Curcumin, a natural compound, no company can reap the benefits if Turmeric shows itself to be an effective anti-cancer drug..." This is unfortunate for pharmaceutical manufacturers who pass promotional and advertising fees to their customers, but good news if you're an educated consumer who doesn't want to pay $20.00 per prescribed pill. Other companies such as "Protandim", "Curamin" and "Juvenon" sell a "patented formula" which contains an undisclosed amount of Turmeric and can cost more than $2.00 per pill.

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PostPosted: Fri Oct 16, 2009 10:33 pm 

Joined: Tue Feb 03, 2009 4:27 pm
Posts: 483
Location: Corneto di Toano, Italy
I bought my turmeric on the 'fresh' market... Cannot remember if it was in Leuven or in Brussels, but it was definitely not in a shop.

Maybe check your local markets too?
Look for the stalls where they have lots of herbs, more the sort of mediterranean stall.
You will have a big chance there to find bags of minimum 250gr for a very cheap price.

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PostPosted: Sat Oct 17, 2009 9:54 am 
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Oe, I should check out the "Albert Cuyp" in Amsterdam, there's a little shop there (including marketspace as always on Albert Cuyp) that has a lot of herbs... or is it just tea? I'm not sure... Thanks for this opening... market... how could I forget. I'm willing to give it a fair try!

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PostPosted: Sun Oct 18, 2009 2:01 am 

Joined: Fri Nov 07, 2008 2:02 pm
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Location: UK Worcester/Hereford border
From The Horse.com
Osteoarthritis: Turmeric Spice Might Provide Natural Remedy
by: Stacey Oke, DVM, MSc
October 13 2009, Article # 15043

Curcumin, an extract of the spice turmeric, is a natural product with potent anti-inflammatory properties that also exerts beneficial effects on cartilage metabolism. Scientists believe curcumin inhibits degradative enzymes such as metalloproteinases and cyclooxygenase-2 (COX-2) and reduces cartilage cell apoptosis (programmed cell death).

To study the effect of curcumin on cartilage breakdown in vitro (in the laboratory), a research team from the University of Nottingham established a model of cartilage inflammation that mimics the inflammatory events thought to occur in osteoarthritis. They induced cartilage degeneration with the pro-inflammatory mediator IL-1 beta. Then they co-treated some cultures with curcumin (0.1-100 µmol/L) for five days, subsequently measuring the amount of glycosaminoglycans (GAG) released from the cartilage in the culture media.

Curcumin significantly reduced the IL-1 beta-stimulated release of GAG back to control levels. Specifically, cartilage explants exposed to 100 µl curcumin reduced GAG release by an average of 20% to 27% when co-exposed to 10 and 25ng/ml IL-1 beta, respectively.

As a result, the authors suggested "curcumin antagonizes GAG release in vitro" and that "this model may be an effective in vitro system for evaluating the potential beneficial effects of botanical extracts."

Investigators indicated the need for more research to determine the "true efficacy and potential safety" of curcumin.

The study, "Interleukin-1 beta–induced extracellular matrix degradation and glycosaminoglycans release is inhibited by curcumin in an explant model of cartilage inflammation," was published in the August 2009 edition of the journal Annals of the New York Academy of Sciences. The abstract is available online.

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PostPosted: Sun Oct 18, 2009 1:23 pm 
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Well I found a internetshop in Dutch that will sell "geelwortelpoeder" which should be the same (they even say so) so can't wait to get it home and see :D

Edit: There's even a store in my hometown that sells it per gram... soon I'll be starting!

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